if you want to develop for the iPhone using an older PPC-based Mac (running 10.5+), there is a way. the guys over at 3x9 and TBradford.org have a good summary of what works. essentially, you should do the following:
/Developer/Platforms/iPhoneSimulator.platform/Developer/
Library/Xcode/Specifications/iPhone Simulator Architectures.xcspec. i didn't even get into the nitty-gritty, but rather, just downloaded the version of the file Tom Bradford posted here and replaced the original (AFTER I BACKED MY ORIGINAL UP!). have fun...
UPDATE: i'm currently not able to debug on my iPhone from the PPC-based Mac. but the simulator runs just fine. i'll update with more details if i figure it out.